Nail Fungus

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Nail Fungus Biography

I have a friend who's so embarrassed about her nail fungus that no one is allowed to see her feet. Her feet are always covered with socks, slippers, shoes or water shoes (if she's at the beach or pool).

Nail fungal infections affect about 12 percent of people living in the United States, and toenail fungus is common in people who have diabetes. Toenail fungus has an inherited tendency and commonly runs in families. Besides being cosmetically unattractive, nail fungal infections can cause nail deformity, pain or discomfort while wearing shoes and odor. And it can lead to more serious foot complications if a secondary infection develops.

If treatment is prescribed, it's important to know that due to the thickness of toenail beds topical medications aren't absorbed easily. You must be persistent with topical medications, applying them daily for up to one year, and even this may not be effective in clearing up the infection.

Oral antifungal drugs can be effective, but they may cause side effects ranging from skin rashes to liver failure. And they aren't recommended for those with liver disease, heart failure or who are taking certain medications.

Recurrent infections are possible if feet are exposed to warm and moist conditions. Remember, keep nails trimmed, free of snags, clean and dry.(By Balaseshan) Apricus Biosciences Inc. (NASDAQ:APRI : 2.6, -0.09) said it will obtain regulatory guidance from Health Canada for MycoVa, its topical treatment for onychomycosis or nail fungus, in a Pre-New Drug Submission meeting scheduled on July 18.

Health Canada has granted the company's request for a Pre-New Drug Submission meeting. Apricus Biosciences expects to obtain feedback from the agency regarding the suitability of its Phase 3 development program to support a New Drug Submission in Canada.

The company expects the upcoming meeting to provide valuable regulatory guidance and would enable it to determine the next steps toward its goal of approval and commercialization of MycoVa in the Canadian market.

In addition, the company is seeking guidance from the U.S. Food and Drug Administration and will be filing for guidance from the European Health Agency.

Apricus Biosciences is currently partnered with Stellar Pharmaceuticals Inc. for the commercialization and marketing of MycoVa in Canada following receipt of regulatory approval by Health Canada.

MycoVa is a topically applied formulation of terbinafine hydrochloride, a well-known medication for nail fungus, delivered with Dodecyl dodecyl 2-(N, N dimethylamino)-propionate hydrochloride, Apricus Bio's proprietary NexACT delivery technology, which enhances absorption of drugs through the skin and other barriers including the nail plate and nail bed.

The company believes MycoVa clinical trials have exhibited a significant mycological effect to eradicate the fungus and also has successfully demonstrated non-inferiority compared to Loceryl, the current topical standard of care for onychomycosis in Europe.

In addition, Apricus Biosciences believes the safety profile of topical terbinafine is significantly improved and much better tolerated than oral terbinafine, which is limited in use to some patients due to its potential for liver toxicity.

APRI is trading down 1.08% at $2.74 on Friday. The stock has been trading between $2.34 and $5.95 for the past 52 weeks.We brought this product on because of the rave reviews.  The ingredients that are used are a combination of the most powerful anti fungals that also go after any secondary bacterial infections. Most cream only ever tackle one. This toenail fungus cream goes after both to kill the supply of the fungus.
Expect clear nails to start showing up in about 3 to 4 weeks. But more importantly watch the yellow, thickened nail that can also have black green under the nail, it will start to clear very shortly. As the nail grows out more and more clear nail will show up.
What Makes This Nail Fungus Cream Different?
It tackles both the fungal and bacterial issues with toenail infections. It uses emu oil to help soak in around and under the nail where fungus hides. It uses 3 powerful anti septic agents that are known to destroy fungus and bacteria. The two often go hand in had yet most creams on the market only treat one. This cream is ph balanced to correct the ph of the toenail to help prevent the growth of more or future fungus. (Most creams do not do this - most creams are ph wrong and have a ph that actually encourage the growth of fungus)
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